課程名稱 |
環境毒理學概論 PRINCIPLES OF ENVIRONMENTAL TOXICOLOGY |
開課學期 |
98-1 |
授課對象 |
公共衛生學院 環境衛生研究所 |
授課教師 |
林靖愉 |
課號 |
EH5019 |
課程識別碼 |
844EU1280 |
班次 |
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學分 |
2 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四5,6(12:20~14:10) |
上課地點 |
公衛210 |
備註 |
本課程以英語授課。 總人數上限:27人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/981EnvTox |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
The course first introduces basic principles of toxicology. Physicochemical properties of toxicants following fate processes (absorption, distribution, metabolism, and elimination), toxicokinetics, and toxicodynamics will be introduced. Factors affecting fate and response and mechanisms of toxic action will also be discussed. The course will then introduce fate of chemicals in the environment. Finally, modern techniques in toxicant metabolism and environmental toxicology will be discussed. |
課程目標 |
This is a selective course for students who are interested in environmental toxicology. Principles of toxicology will be first introduced. Fate processes of toxicants in the body, toxicokinetics, toxicodynamics, and mechanism of toxic action will be presented. Fate of chemicals in environment will also be discussed. Students will learn the basic concepts of toxicology and study the whole picture of fate processes of chemicals in both the body and environment. |
課程要求 |
The curse is offered in English. The prerequisite of this course is Organic Chemistry. |
預期每週課後學習時數 |
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Office Hours |
另約時間 備註: by appointment |
指定閱讀 |
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參考書目 |
Casarett & Doull’s Toxicology – The Basic Science of Poisons by Curtis D.
Klaassen
Goodman & Gilman's The Pharmacological Basis of Therapeutics by Laurence L.
Brunton, John S. Lazo, and Keith L. Parker |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
Midterm I |
30% |
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2. |
Midterm II |
30% |
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3. |
Final |
35% |
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4. |
Homework |
5% |
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週次 |
日期 |
單元主題 |
第1週 |
09/17 |
Introduction; Principles of toxicology |
第2週 |
09/24 |
Physicochemical properties of toxicants |
第3週 |
10/01 |
Fate processes in the body –absorption, distribution |
第4週 |
10/08 |
Fate processes in the body –metabolism |
第5週 |
10/15 |
Fate processes in the body –elimination |
第6週 |
10/22 |
Midterm I |
第7週 |
10/29 |
Toxicokinetics, PBPK |
第8週 |
11/05 |
Factors affecting fate and response |
第9週 |
11/12 |
Toxicodynamics |
第10週 |
11/19 |
Mechanisms of toxic action |
第11週 |
11/26 |
Mechanisms of toxic action |
第12週 |
12/03 |
Midterm exam II |
第13週 |
12/10 |
Fate processes in environment - chemical principles |
第14週 |
12/17 |
Fate processes in environment - biological applications |
第15週 |
12/24 |
Modern techniques in toxicant metabolism |
第16週 |
12/31 |
Toxicogenomic technologies |
第17週 |
01/07 |
Review |
第18週 |
01/14 |
Final exam |
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